Modeling neurodegeneration in Caenorhabditis elegans
نویسندگان
چکیده
منابع مشابه
Gas-Induced Neurodegeneration in Caenorhabditis elegans
We describe a genetic model for neurodegeneration in the nematode Caenorhabditis elegans. Constitutive activation of the GTP-binding protein Gas induces neurodegeneration. Neuron loss occurs in two phases whereby affected cells undergo a swelling response in young larvae and subsequently die sometime during larval development. Different neural cell types vary greatly in their susceptibility to ...
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ژورنال
عنوان ژورنال: Disease Models & Mechanisms
سال: 2020
ISSN: 1754-8411,1754-8403
DOI: 10.1242/dmm.046110